Analysis of age-related global DNA methylation in chicken
Biochemical Genetics, ISSN: 0006-2928, Vol: 51, Issue: 7-8, Page: 554-563
2013
- 37Citations
- 61Captures
- 3Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations37
- Citation Indexes36
- 36
- CrossRef21
- Patent Family Citations1
- Patent Families1
- Captures61
- Readers61
- 61
- Mentions3
- References3
- Wikipedia3
Article Description
DNA methylation is an epigenetic modification that plays an important role in the normal development and function of organisms. The level of DNA methylation is species-, tissue-, and organelle-specific, and the methylation pattern is determined during embryogenesis. DNA methylation has also been correlated with age. The aim of this study was to determine the global DNA methylation levels and their correlation with age in the chicken, using a Polish autosexing chicken breed, Polbar. A quantitative technique based on an immunoenzymatic assay was used for global DNA methylation analysis. The results show increased global DNA methylation levels with older Polbar embryos. Global DNA methylation levels decrease with the age of hens in the postembryonic stage. This study expands the current knowledge of the Polbar epigenome and the general knowledge of the function of epigenetic mechanisms in birds. © 2013 The Author(s).
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84880603979&origin=inward; http://dx.doi.org/10.1007/s10528-013-9586-9; http://www.ncbi.nlm.nih.gov/pubmed/23553491; http://link.springer.com/10.1007/s10528-013-9586-9; https://dx.doi.org/10.1007/s10528-013-9586-9; https://link.springer.com/article/10.1007/s10528-013-9586-9
Springer Science and Business Media LLC
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