2-And 3-phenylsulfonylindoles-synthetic equivalents of unsubstituted indole in n-alkylation reactions
Chemistry of Heterocyclic Compounds, ISSN: 0009-3122, Vol: 46, Issue: 3, Page: 291-301
2010
- 11Citations
- 6Captures
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Article Description
The N-alkylation of 2- and 3-phenylsulfonylindoles under various conditions and the subsequent removal of the activating phenylsulfonyl group by reductive desulfonylation using Raney nickel leads to N-alkylindoles in high yield. 2-Phenylsulfonylindole readily undergoes the Mitsunobu reaction, while isomeric 3-phenylsulfonylindole is relatively inert under these conditions. © 2010 Springer Science+Business Media, Inc.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77956486012&origin=inward; http://dx.doi.org/10.1007/s10593-010-0504-3; http://link.springer.com/10.1007/s10593-010-0504-3; http://link.springer.com/content/pdf/10.1007/s10593-010-0504-3; http://link.springer.com/content/pdf/10.1007/s10593-010-0504-3.pdf; http://link.springer.com/article/10.1007/s10593-010-0504-3/fulltext.html; http://www.springerlink.com/index/10.1007/s10593-010-0504-3; http://www.springerlink.com/index/pdf/10.1007/s10593-010-0504-3; https://dx.doi.org/10.1007/s10593-010-0504-3; https://link.springer.com/article/10.1007/s10593-010-0504-3
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