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Reaction of N-(3-oxoalkenyl)chloroacetamides with sodium p-toluenesulfinate – synthesis of 3-tosylpyridin-2(1Н)-ones

Chemistry of Heterocyclic Compounds, ISSN: 1573-8353, Vol: 53, Issue: 12, Page: 1335-1339
2017
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[Figure not available: see fulltext.] A series of N-(3-oxoalkenyl)chloroacetamides was prepared by acylation of β-enaminoketones with chloroacetyl chloride. A reaction of these compounds with sodium p-toluenesulfinate in dimethylformamide in the presence of potassium carbonate led to 3-tosylpyridin-2(1H)-ones. The limitations of this reaction were studied.

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