Posterior wall isolation in persistent atrial fibrillation. Long-term outcomes of a repeat procedure strategy
Journal of Interventional Cardiac Electrophysiology, ISSN: 1572-8595, Vol: 66, Issue: 4, Page: 971-979
2023
- 7Citations
- 5Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations7
- Citation Indexes7
- Captures5
- Readers5
- Mentions1
- News Mentions1
- 1
Most Recent News
New Atrial Fibrillation Study Findings Recently Were Reported by Researchers at Copenhagen University Hospital Gentofte (Posterior Wall Isolation In Persistent Atrial Fibrillation. Long-term Outcomes of a Repeat Procedure Strategy)
2022 DEC 02 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Cardiovascular Daily -- A new study on Heart Disorders and Diseases -
Article Description
Background: Posterior wall isolation (PWI) added to pulmonary vein isolation (PVI) is increasingly used in ablation for persistent atrial fibrillation (PeAF) despite limited evidence of clinical benefit. We investigated the 5-year outcomes of a PVI + PWI ablation strategy with mandatory repeat procedures in PeAF. Methods: Twenty-four patients with PeAF participated in this single-arm prospective study and underwent radiofrequency ablation (RFA) with wide area circumferential ablation (WACA), roof, and inferior lines for PVI + PWI which was reinforced if required during mandated repeat procedures after 6 months. Then, patients were followed for 60 months using continuous heart rhythm monitoring by implanted cardiac monitors (ICM) and atrial fibrillation effect on quality-of-life scoring (AFEQT; range: 20–100 points) for the initial 30 months. Results: ICM-verified cumulated AF recurrence was 54% after 30 months but the ensuing AF burden was only median 0‰ [0 to 4.8‰] overall and 1‰ [0 to 8 ‰] among patients with any recurrence. AFEQT scores increased from baseline 60 points [48 to 72] to 93 points [84 to 96] at repeat procedures P < 0.0001 and further to 96 points [93 to 99] P = 0.03 after 30 months. After 60 months, at least one episode of AF had been documented in 63% and two patients (8%) were in permanent AF. Conclusion: Reinforced PVI + PWI was associated with low long-term AF burden and corresponding improvements in quality-of-life. Reinforced (or durable) PVI + PWI appears to be a promising strategy to treat PeAF. Trial registration: ClinicalTrials.gov. Identifier: NCT05045131.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85141184292&origin=inward; http://dx.doi.org/10.1007/s10840-022-01402-x; http://www.ncbi.nlm.nih.gov/pubmed/36327059; https://clinicaltrials.gov/ct2/show/NCT05045131; https://link.springer.com/10.1007/s10840-022-01402-x; https://dx.doi.org/10.1007/s10840-022-01402-x; https://link.springer.com/article/10.1007/s10840-022-01402-x
Springer Science and Business Media LLC
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