A polyrotaxane gel using boronic acid-appended γ-cyclodextrin as a hybrid cross-linker
Journal of Inclusion Phenomena and Macrocyclic Chemistry, ISSN: 1573-1111, Vol: 89, Issue: 3-4, Page: 281-288
2017
- 7Citations
- 19Captures
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Article Description
A boronic acid-appended γ-cyclodextrin (BA-CyD) was synthesized as a hybrid cross-linker of polyvinyl alcohol (PVA) to form a new type of hydrogel. The CyD moiety of BA-CyD forms an inclusion complex with the PVA chain to produce a mechanically interlocking structure. At the same time, the BA moiety of BA-CyD forms covalent bonds with the 1,3-diol moieties of PVA. On the basis of these two modes of interaction, the hybrid cross-linker connects two PVA chains, thus resulting in the formation of a hydrogel. To investigate the possibility of this hydrogel becoming the basis for an intelligent material for drug delivery, sugar-responsive drug release from the hydrogel was demonstrated.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85033486758&origin=inward; http://dx.doi.org/10.1007/s10847-017-0755-z; http://link.springer.com/10.1007/s10847-017-0755-z; http://link.springer.com/content/pdf/10.1007/s10847-017-0755-z.pdf; http://link.springer.com/article/10.1007/s10847-017-0755-z/fulltext.html; https://dx.doi.org/10.1007/s10847-017-0755-z; https://link.springer.com/article/10.1007/s10847-017-0755-z
Springer Nature
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