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Study of the Anticancer Activity of a New Nanosize Bismuth(V)-Based Coordination Complex Against Human Bone Tumor Cells

Journal of Chemical Crystallography, ISSN: 1572-8854, Vol: 51, Issue: 4, Page: 553-561
2021
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Article Description

Herein we report a new bismuth(V)-based coordination complex Bi(phenyl)(2,5-dfa) (1) that has been successfully prepared by using C donor phenyl ring and O donor 2,5-difluorobenzoic acid (2,5-Hdfa) ligands. The coordination complex has been comprehensively characterized by single crystal X-ray diffraction, Powder X-ray diffraction and thermogravimetric analysis. Finally, an evaluation of cytotoxicity against human OS-732 bone tumor cell lines for the synthesized nanoparticles was performed. Graphic Abstract: A new bismuth(V)-based coordination complex Bi(phenyl)(2,5-dfa) (1) has been successfully prepared and evaluation of cytotoxicity against human OS-732 bone tumor cell lines for its related nanoparticles was performed.[Figure not available: see fulltext.].

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