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Antioxidant and Anticancer Properties of Biosynthesized GA/Ag-FeO@ Nanocomposites

Journal of Cluster Science, ISSN: 1572-8862, Vol: 33, Issue: 3, Page: 903-911
2022
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Article Description

The current work reports a simple and cost-effective green method for fabricating MEL@FeONPs and GA/Ag–FeO@MEL-NCs using microbial glycolipid mannosylerythritol lipids (MEL) and gum arabic. The prepared bionanocomposites were characterized using X-ray diffraction analysis (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS), and Fourier-transform infrared spectroscopy (FTIR). TEM analysis of the bionanocomposites showed the spherical shape particles. Furthermore, the GA/Ag–FeO@MEL-NCs showed potent antioxidant efficacy against DPPH, ABTS, and FRAP (IC; 62.95, 70.63, and 63.26 µg/mL, respectively). Moreover, the IC values of biosynthesized MEL@FeO and GA/Ag–FeO@MEL-NCs for inhibition human liver cancer cells were 119.35 and 85.18 µg/mL, respectively, indicating its greater efficacy in killing cancer cells. As-prepared GA/Ag–FeO@MEL-NCs may have great potential application in the field of pharmaceuticals as nanoantioxidants and anti-hepatocarcinoma.

Bibliographic Details

Abdelmoneim Bakur; Lu Hongyun; Dafaallah Albashir; Qihe Chen; Tarig Elshaarani; Anas Mohammed

Springer Science and Business Media LLC

Chemistry; Biochemistry, Genetics and Molecular Biology; Materials Science; Physics and Astronomy

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