Evaluation of an automated synthesis method for [F]Fluoromisonidazole using a Scintomics GRP® module
Journal of Radioanalytical and Nuclear Chemistry, ISSN: 1588-2780, Vol: 333, Issue: 11, Page: 5889-5898
2024
- 7Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Captures7
- Readers7
Article Description
There is limited information on utilizing commercially supplied [F]Fluoride from an off-site cyclotron for the synthesis of radiopharmaceuticals. This study explored the production of the PET hypoxia marker [F]FMISO, using the Scintomics® GRP module and distantly produced [F]Fluoride, which lacks published data. A radiochemical yield of 27.4 ± 3.6% (n = 5) and high radiochemical purity were achieved in synthesis time of 48 min. The [F]FMISO met all Ph. Eur. standards, demonstrating the consistency and reliability of the module in generating a clinical-grade radiopharmaceutical using off-site produced [F]Fluoride, but available patient doses were severely limited.
Bibliographic Details
Springer Science and Business Media LLC
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