Altered membrane free unsaturated fatty acid composition in human colorectal cancer tissue
Molecular and Cellular Biochemistry, ISSN: 0300-8177, Vol: 294, Issue: 1-2, Page: 237-242
2007
- 35Citations
- 24Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations35
- Citation Indexes35
- 35
- CrossRef26
- Captures24
- Readers24
- 24
Article Description
Polyunsaturated free fatty acids (PUFAs) participate in normal functioning of the cell, particularly in control intracellular cell signalling. As nutritional components they compose a human diet with an indirect promoting influence on tumourogenesis. The PUFAs level depends on the functional state of the membrane. This work is focused on changes only of free unsaturated fatty acids amount (AA - arachidonic acid, LA - linoleic acid, ALA - α- linolenic acid, palmitoleic acid (PA) and oleic acid) in cell membranes of colorectal cancer of pT3 stage, G2 grade without metastasis. Qualitative and quantitative composition of free unsaturated fatty acids in the membrane was determined by high-performance liquid chromatography. It was shown that the malignant transformation was accompanied by a decrease in amount of LA and ALA while arachidonic and oleic acids increased. It is of interest that free AA levels are elevated in colon cancer, as AA is the precursor to biologically active eicosanoids. © Springer Science+Business Media, Inc. 2006.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33846670434&origin=inward; http://dx.doi.org/10.1007/s11010-006-9264-x; http://www.ncbi.nlm.nih.gov/pubmed/16858511; http://link.springer.com/10.1007/s11010-006-9264-x; http://www.springerlink.com/index/10.1007/s11010-006-9264-x; http://www.springerlink.com/index/pdf/10.1007/s11010-006-9264-x; https://dx.doi.org/10.1007/s11010-006-9264-x; https://link.springer.com/article/10.1007/s11010-006-9264-x
Springer Science and Business Media LLC
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