DNA-templated synthesis optimization
Natural Computing, ISSN: 1572-9796, Vol: 17, Issue: 4, Page: 693-707
2018
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
In chemistry, synthesis is the process in which a target compound is produced in a step-wise manner from given base compounds. A recent, promising approach for carrying out these reactions is DNA-templated synthesis, since, as opposed to more traditional methods, this approach leads to a much higher effective molarity and makes much desired (sequential) one-pot synthesis possible. With this method, compounds are tagged with DNA sequences and reactions can be controlled by bringing two compounds together via their tags. This leads to new cost optimization problems of minimizing the number of different tags or strands to be used under various conditions. We identify relevant optimization criteria, provide the first computational approach to automatically inferring DNA-templated programs, and obtain efficient optimal and near-optimal results, and also provide a brute-force integer linear programming approach for complete solutions to smaller instances.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85051444058&origin=inward; http://dx.doi.org/10.1007/s11047-018-9697-7; http://link.springer.com/10.1007/s11047-018-9697-7; http://link.springer.com/content/pdf/10.1007/s11047-018-9697-7.pdf; http://link.springer.com/article/10.1007/s11047-018-9697-7/fulltext.html; https://dx.doi.org/10.1007/s11047-018-9697-7; https://link.springer.com/article/10.1007/s11047-018-9697-7
Springer Science and Business Media LLC
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