A current update on phytochemistry, pharmacology and herb–drug interactions of Hypericum perforatum
Phytochemistry Reviews, ISSN: 1572-980X, Vol: 16, Issue: 4, Page: 725-744
2017
- 43Citations
- 104Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Review Description
Hypericum perforatum L. is an ethnomedicine with a popular remedial legacy; especially of antidepressant and wound healing properties. Rigorous preclinical and clinical research conducted in last sesqui-decade has revealed newer facets of its therapeutic activities against psychiatric, metabolic and neoplastic disorders. Most of such curative effects are imparted synergistically by hypericin, hyperforin and flavonoids; but their action mechanisms remain ambiguous. Concomitant administration of St. John’s Wort formulation and cytochrome P450 substrate drug is limited by the episodes of herb–drug interactions; nevertheless, adverse drug reaction rate of H. perforatum remains only 2%. In present review, we aim to highlight the ‘evidence-based’ therapeutic potential of aforementioned phytopharmaceutical, which would accelerate the contemporary pharmaceutical development of this traditional phytomedicine.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85017109000&origin=inward; http://dx.doi.org/10.1007/s11101-017-9503-7; http://link.springer.com/10.1007/s11101-017-9503-7; http://link.springer.com/content/pdf/10.1007/s11101-017-9503-7.pdf; http://link.springer.com/article/10.1007/s11101-017-9503-7/fulltext.html; https://dx.doi.org/10.1007/s11101-017-9503-7; https://link.springer.com/article/10.1007/s11101-017-9503-7
Springer Science and Business Media LLC
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know