PlumX Metrics
Embed PlumX Metrics

Perfluoroalkyl substance (PFAS) exposure and risk of nonalcoholic fatty liver disease in the elderly: results from NHANES 2003–2014

Environmental Science and Pollution Research, ISSN: 1614-7499, Vol: 30, Issue: 23, Page: 64342-64351
2023
  • 19
    Citations
  • 0
    Usage
  • 18
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

Findings on Non-Alcoholic Fatty Liver Disease Detailed by Investigators at Department of Hepatobiliary Surgery [Perfluoroalkyl Substance (Pfas) Exposure and Risk of Nonalcoholic Fatty Liver Disease In the Elderly: Results From Nhanes 2003-2014]

2023 JUL 03 (NewsRx) -- By a News Reporter-Staff News Editor at Gastroenterology Daily News -- A new study on Liver Diseases and Conditions -

Article Description

This study aimed to investigate the association between perfluoroalkyl substance (PFAS) exposure and the risk of nonalcoholic fatty liver disease (NAFLD) in the elderly. Our sample included 1420 participants (≥ 60 years) from the 2003–2014 NHANES study with available serum PFASs, covariates, and outcomes. NAFLD was defined based on the hepatic steatosis index. Weighted binary logistic regression was utilized to calculate the odds ratio (OR) and 95% confidence intervals for each chemical. Results suggested that increase in PFOA concentrations was positively associated with risk of NAFLD in adjusted models. PFNA was also significantly associated with NAFLD development in adjusted linear regression. The effect of PFOA or PFNA on NAFLD development was found to be linear in the trend test. This study added novel evidence that exposure to PFASs (PFOA and PFNA) might be associated with NAFLD development.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know