Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives
Journal of Natural Medicines, ISSN: 1861-0293, Vol: 68, Issue: 3, Page: 465-472
2014
- 48Citations
- 59Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations48
- Citation Indexes48
- 48
- CrossRef12
- Captures59
- Readers59
- 59
Article Description
Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous studies with β-PGG revealed a wide variety of biological activities, such as anti-microbial and anti-cancer functions. Until recently, studies with α-PGG were limited by the lack of its availability. Since the development of an efficient chemical synthesis of the compound, several investigations have revealed its anti-diabetic, anti-cancer, and anti-platelet-coagulation functions. Based on structure-activity-relationship (SAR) studies with α-PGG, a variety of α-PGG-related novel compounds were synthesized and some of them have been shown to possess promising therapeutic activities. In this review, the authors will survey and evaluate the biological functions of PGG with a focus on α-PGG and its derivatives. © 2014 The Japanese Society of Pharmacognosy and Springer.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84904639309&origin=inward; http://dx.doi.org/10.1007/s11418-014-0823-2; http://www.ncbi.nlm.nih.gov/pubmed/24532420; http://link.springer.com/10.1007/s11418-014-0823-2; https://dx.doi.org/10.1007/s11418-014-0823-2; https://link.springer.com/article/10.1007/s11418-014-0823-2
Springer Science and Business Media LLC
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