Complicated evolutionary patterns of microRNAs in vertebrates
Science in China, Series C: Life Sciences, ISSN: 1006-9305, Vol: 51, Issue: 6, Page: 552-559
2008
- 3Citations
- 11Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations3
- Citation Indexes3
- CrossRef2
- Captures11
- Readers11
- 11
Article Description
MicroRNAs (miRNAs) are a class of ∼22 nt long endogenous non-coding RNAs that play important regulatory roles in diverse organisms. Up to now, little is known about the evolutionary properties of these crucial regulators. Most miRNAs were thought to be phylogenetically conserved, but recently, a number of poorly-conserved miRNAs have been reported and miRNA innovation is shown to be an ongoing process. In this work, through the characterization of an miRNA super family, we studied the evolutionary patterns of miRNAs in vertebrates. Recently generated miRNAs seem to evolve rapidly during a certain period following their emergence. Multiple lineage-specific expansions were observed. Homolgous premiRNAs may produce mature products from the opposite stem arms following tandem duplications, which may have important contribution to miRNA innovation. Our observations of miRNAs' complicated evolutionary patterns support the notion that these key regulatory molecules may play very active roles in evolution. © 2008 Science in China Press and Springer-Verlag GmbH.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=44049107810&origin=inward; http://dx.doi.org/10.1007/s11427-008-0075-z; http://www.ncbi.nlm.nih.gov/pubmed/18488176; http://link.springer.com/10.1007/s11427-008-0075-z; https://dx.doi.org/10.1007/s11427-008-0075-z; https://link.springer.com/article/10.1007/s11427-008-0075-z
Springer Science and Business Media LLC
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