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Importance of the heart rate in ultra-high-resolution coronary CT angiography with 0.35 s gantry rotation time

Japanese Journal of Radiology, ISSN: 1867-108X, Vol: 40, Issue: 8, Page: 781-790
2022
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Article Description

Purpose: We investigated the effects of the heart rate (HR) on the motion artifact in coronary computed tomography angiography (CCTA) with ultra-high-resolution-CT (U-HRCT), and we clarified the upper limit of optimal HR in CCTA with U-HRCT in a comparison with conventional-resolution-CT (CRCT) on a cardiac phantom and in patients with CCTA. Materials and methods: A pulsating cardiac phantom equipped with coronary models was scanned at static and HR simulations of 40–90 beats/min (bpm) at 10-bpm intervals using U-HRCT and CRCT, respectively. The sharpness and lumen diameter of the coronary model were quantitatively compared between U-HRCT and CRCT stratified by HR in the phantom study. We also assessed the visual inspections of clinical images in CCTA with U-HRCT. Results: At the HRs ≤ 60 bpm, the error of the lumen diameter of the U-HRCT tended to be smaller than that of the CRCT. However, at the HRs > 60 bpm, the inverse was shown. For the image sharpness, the U-HRCT was significantly superior to the CRCT (p < 0.05). In the visual assessment, the scores were negatively correlated with HRs in patients (Spearman r = − 0.71, p < 0.01). A receiver-operating characteristic analysis revealed the HR of 61 bpm as the optimal cutoff of the non-diagnostic image quality, with an area under the curve of 0.87, 95% sensitivity, and 71% specificity. Conclusion: At HRs ≤ 60 bpm, U-HRCT was more accurate in the imaging of coronary arteries than CRCT. The upper limit of the optimal HR in CCTA with U-HRCT was approx. 60 bpm.

Bibliographic Details

Kojima, Tsukasa; Shirasaka, Takashi; Yamasaki, Yuzo; Kondo, Masatoshi; Hamasaki, Hiroshi; Mikayama, Ryoji; Sakai, Yuki; Kato, Toyoyuki; Nishie, Akihiro; Ishigami, Kousei; Yabuuchi, Hidetake

Springer Science and Business Media LLC

Medicine

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