RETRACTED ARTICLE: Colorectal Infraperitoneal Anastomosis: The Effects of Perioperative Supplemental Oxygen Administration on the Anastomotic Dehiscence
Journal of Gastrointestinal Surgery, ISSN: 1091-255X, Vol: 16, Issue: 2, Page: 427-434
2012
- 46Citations
- 75Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations46
- Citation Indexes44
- 44
- CrossRef43
- Clinical Citations1
- PubMed Guidelines1
- Policy Citations1
- Policy Citation1
- Captures75
- Readers75
- 75
- Mentions1
- Blog Mentions1
- Blog1
Review Description
The role of supplemental oxygen therapy in the healing of colorectal anastomosis is still very much at an experimental stage. The aim of the present study, prospective randomized, was to assess the effect of administration of perioperative supplemental oxygen therapy on infraperitoneal anastomosis, where the risk of leakage is higher. We enrolled 72 patients between February, 2008 and February, 2011, who underwent elective open infraperitoneal anastomosis for rectal cancer (middle and low). Patients were assigned randomly to an oxygen/air mixture with a fraction of inspired oxygen (FiO 2 ) of 30% ( n = 37) or 80% ( n = 35). Administration was commenced after induction of anesthesia and maintained for 6 h after surgery. The overall anastomotic leak rate was 16.6% (12 out of 72); 8 patients (21.6%) had an anastomotic dehiscence in the 30% FiO 2 group and 4 (11.4%) in the 80% FiO 2 group ( p < 0.05). The risk of anastomotic leak was 46% lower in the 80% FiO 2 group (RR, 0.63; 95% confidence interval, 0.42–0.98) vs. the 30% FiO 2. Therefore, supplemental 80% FiO 2 during and for 6 h after major rectal cancer surgery, reducing postoperative anastomotic dehiscence, should be considered part of ongoing quality improvement activities related to surgical care, with few risks to the patient and little associated cost.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1091255X2303679X; http://dx.doi.org/10.1007/s11605-011-1717-1; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84856232258&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/21975687; https://linkinghub.elsevier.com/retrieve/pii/S1091255X2303679X; https://dx.doi.org/10.1007/s11605-011-1717-1
Elsevier BV
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