Xiaoke Pill (消渴丸) and anti-diabetic drugs: A review on clinical evidence of possible herb-drug interactions
Chinese Journal of Integrative Medicine, ISSN: 1993-0402, Page: 1-8
2016
- 7Citations
- 36Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations7
- Citation Indexes7
- Captures36
- Readers36
- 36
Article Description
Objective: To critically analyze the clinically-based evidence of herb-drug interaction on Xiaoke Pill (消渴丸) and its concomitant use with anti-diabetic drugs. Methods: MEDLINE, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Allied and Complementary Medicine Database (AMED), International Pharmaceutical Abstracts (IPA), Chinese BioMedical Literature Database (CBM), Traditional Chinese Medical Database System (TCMDS), China National Knowledge Infrastructure Database (CNKI) and Wangfang Databases were searched. Levels of Evidence and Severity Level of Interaction were used to evaluate the quality of the included studies. Results: A total of 27 studies published in Chinese, including 2 randomized controlled trials, 3 case series and 22 case reports, were included. Eighteen herbdrug interactions were reported involving Xiaoke Pill as monotherapy, while 6 herb-drug interactions occurred associated with Xiaoke Pill in combination with anti-diabetic drugs. The clinical results of herb-drug interaction of Xiaoke Pill were reported as additive blood glucose-lowering effects with anti-diabetic drugs, including benefifi cial and adverse hypoglycemic effects, anaphylactic shock and severe hair loss. Of these interactions 82.8% were reported to be associated with potential deterioration of the patients’ conditions including hypoglycemic coma, stroke, mental disorder and even death. Conclusions: This review helped establish the clinically-based evidence about herb-drug interaction of Xiaoke Pill and its concomitant use with anti-diabetic drugs. The fifi ndings would help arouse the awareness of both health professionals and the general public to avoid the adverse herb-drug interactions of Xiaoke Pill in healthcare and community settings.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84955558139&origin=inward; http://dx.doi.org/10.1007/s11655-015-2106-5; http://www.ncbi.nlm.nih.gov/pubmed/26825080; http://link.springer.com/10.1007/s11655-015-2106-5; https://dx.doi.org/10.1007/s11655-015-2106-5; https://link.springer.com/article/10.1007/s11655-015-2106-5
Springer Science and Business Media LLC
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