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Molecular analysis for medicine: A new technological platform based on nanopatterning and label free optical direction

Bio Tribune Magazine, ISSN: 1951-655X, Vol: 33, Issue: 1, Page: 31-35
2009
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Article Description

In this contribution, we show that by biopatterning probe molecules at the nanoscale using soft-lithography, we can produce protein biochips at a cost sufficiently small for their use as a systematic method of molecular analysis for medical diagnosis purposes. The combination of multiplexed nanoscale Micro-Contact printing and label-free optical detection using the principle of light diffraction, is implemented for generating engineered glass slides of analysis and a dedicated diffractive scanner for reading the multiplexed results of an assay. © 2009 Springer Verlag France.

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