PlumX Metrics
Embed PlumX Metrics

Ivabradine, Coronary Heart Disease, and Heart Failure: Time for Reappraisal

Current Atherosclerosis Reports, ISSN: 1534-6242, Vol: 16, Issue: 12, Page: 1-4
2014
  • 5
    Citations
  • 0
    Usage
  • 6
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Review Description

Ivabradine is generally considered to be a safe drug with well-established and substantial benefits. Nevertheless, recently published results from the SIGNIFY trial suggest that ivabradine has rather inconsistent effects on cardiovascular outcomes. In addition, careful examination of all available data from ivabradine trials reveals signals of harm that have not yet been appropriately addressed, including a markedly increased incidence of atrial fibrillation and increased risk of cardiovascular events in patients with heart rates below 70 bpm. These concerns warrant consideration, since they could have implications for the future use of ivabradine.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know