PlumX Metrics
Embed PlumX Metrics

The ileal brake: a fifteen-year progress report.

Current gastroenterology reports, ISSN: 1522-8037, Vol: 1, Issue: 5, Page: 404-409
1999
  • 113
    Citations
  • 0
    Usage
  • 92
    Captures
  • 0
    Mentions
  • 5
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    113
  • Captures
    92
  • Social Media
    5
    • Shares, Likes & Comments
      5
      • Facebook
        5

Review Description

The "ileal brake" is the primary inhibitory feedback mechanism to control transit of a meal through the gastrointestinal tract in order to optimize nutrient digestion and absorption. Neurohormonal factors mediating this response continue to be identified. Recently, additional brakes that fine-tune transit have been described. When gut traffic control is disrupted, pathologic states characterized by malabsorption and impaired drug bioavailability manifest as diarrhea and malnutrition. An understanding of the importance of these nutrient-triggered brakes provides essential clues to future treatments of chronic diarrhea, malnutrition, and drug malabsorption.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know