A patient with Leiden v mutation, multiple sclerosis, psoriasis, and sicca syndrome: Could celecoxib and fingolimod adversely affect the heart?
Cardiovascular Toxicology, ISSN: 1530-7905, Vol: 12, Issue: 3, Page: 266-272
2012
- 2Citations
- 62Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations2
- Citation Indexes2
- CrossRef2
- Captures62
- Readers62
- 62
Article Description
The paper describes the case of a patient affected by a combination of genetic and autoimmune diseases (multiple sclerosis, psoriatic arthritis, Leiden V mutation, and sicca syndrome) and hypertension. The psoriatic arthritis was treated with celecoxib and multiple sclerosis with fingolimod. The patient developed high fever and endocarditis, resulting in severe mitral regurgitation, atrial fibrillation, and congestive heart failure. Evidence is suggestive of adverse effects of potent immunosuppressive and anti-inflammatory therapies with biologic agents and the cardiovascular system. Fingolimod increases susceptibility to infections and induced endocarditis resulting in severe mitral regurgitation, atrial fibrillation, and congestive heart failure. Managed care systems limit the contact among basic care physicians and specialists. However, the process by which the optimal decision may be reached for a patient with a complex pathology is shared decision making, where the risk of severe complications and medical expenses may be reduced. © 2011 Springer Science+Business Media, LLC.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864693327&origin=inward; http://dx.doi.org/10.1007/s12012-012-9166-y; http://www.ncbi.nlm.nih.gov/pubmed/22528818; http://link.springer.com/10.1007/s12012-012-9166-y; https://dx.doi.org/10.1007/s12012-012-9166-y; https://link.springer.com/article/10.1007%2Fs12012-012-9166-y; http://www.springerlink.com/index/10.1007/s12012-012-9166-y; http://www.springerlink.com/index/pdf/10.1007/s12012-012-9166-y
Springer Science and Business Media LLC
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