Disodium Anacardate: A Bio-based Catalyst for Room Temperature Synthesis of New, Fluorescent 1, 4-Benzoxazinone and Benzophenoxazinone Derivatives

The first report of room temperature synthesis of new, fluorescent 1, 4-benzoxazinone derivatives using disodium anacardate as a bio-based catalyst is discussed here. Disodium anacardate was derived from cashew nut shell liquid (CNSL) which is a renewable but underutilized agro by-product of the cashew industry. The synthesis of 1, 4-benzoxazinone derivatives were derived through a one-pot three-component reaction of 2-aminophenol, diethyl acetylenedicarboxylate, and trans 1, 2-dibenzoylethylene. Further, the utility of disodium anacardate as a base catalyst is tested effectively for the room temperature synthesis of benzophenoxazinone derivatives synthesized from 2-aminophenol and dichloro-1,4-naphthoquinones. In a solvent effect study, the catalyst activity of disodium anacardate was found excellent in green solvents. The fluorescence activity was studied for the synthesized molecules. Our efforts through this study are to explore the novel applications of anacardic acid in organic transformations and establish its utility in new synthetic methodologies. Graphical abstract: Herein, we report room temperature synthesis of new fluorescent 1,4-benzoxazinone and benzophenoxazinones derivatives using disodium anacardate as a bio-based catalyst which was also synthesized at room temperature from Cashew nut shell liquid (CNSL). The fluorescence activity was studied for the synthesized molecules.[Figure not available: see fulltext.].