One-pot biotransformation of racemic styrene oxide into (R)-1,2-phenylethandiol by two recombinant microbial epoxide hydrolases
Biotechnology and Bioprocess Engineering, ISSN: 1226-8372, Vol: 13, Issue: 4, Page: 453-457
2008
- 23Citations
- 15Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Article Description
An enantioconvergent biotransformation of racemic styrene oxide by using two recombinant microbial epoxide hydrolases (EHs) in one pot has been investigated to prepare enantiopure vicinal diols. The recombinant whole cell possessing EH gene from Aspergillus niger LK or Rhodotorula glutinis exhibited a complementary enantioselectivity and regioselectivity, compared to the recombinant cell containing Caulobacter crescentus EH gene. When two recombinant microbial EHs were used in combination, 1.3 g of enantiopure (R)-1,2-phenylethandiol with more than 90% enantiopurity and 95% overall yield was obtained from 1.2 g of racemic styrene oxide in a preparative-scale batch enantioconvergent biotransformation. © The Korean Society for Biotechnology and Bioengineering and Springer-Verlag Berlin Heidelberg GmbH 2008.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=52749090358&origin=inward; http://dx.doi.org/10.1007/s12257-008-0153-x; http://link.springer.com/10.1007/s12257-008-0153-x; http://link.springer.com/content/pdf/10.1007/s12257-008-0153-x; http://link.springer.com/content/pdf/10.1007/s12257-008-0153-x.pdf; http://link.springer.com/article/10.1007/s12257-008-0153-x/fulltext.html; https://dx.doi.org/10.1007/s12257-008-0153-x; https://link.springer.com/article/10.1007/s12257-008-0153-x; http://www.springerlink.com/index/10.1007/s12257-008-0153-x; http://www.springerlink.com/index/pdf/10.1007/s12257-008-0153-x
Springer Science and Business Media LLC
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