Recent development of highly sensitive Protease assay methods: Signal amplification through enzyme cascades
Biotechnology and Bioprocess Engineering, ISSN: 1976-3816, Vol: 17, Issue: 6, Page: 1113-1119
2012
- 20Citations
- 22Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations20
- Citation Indexes20
- 20
- CrossRef12
- Captures22
- Readers22
- 22
Review Description
Proteases are involved in almost all biological processes, and therefore, aberrant activity of many of these enzymes is an important indicator of disease. Various methods have been developed to analyze protease activity, among which, protease assays based on resonance energy transfer are currently used most widely. However, quantitative methods with relatively higher sensitivity are needed, especially for disease diagnosis at early stages. One of the strategies to achieve higher sensitivity is to implement signal amplification of the protease activity. In this review, we briefly summarize the protease assay methods based on resonance energy transfer, and then elaborate the efforts to develop sensitive protease assays through signal amplification by using enzyme cascades. © The Korean Society for Biotechnology and Bioengineering and Springer 2012.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84879924939&origin=inward; http://dx.doi.org/10.1007/s12257-012-0545-9; http://www.ncbi.nlm.nih.gov/pubmed/32218678; http://link.springer.com/10.1007/s12257-012-0545-9; http://www.springerlink.com/index/10.1007/s12257-012-0545-9; http://www.springerlink.com/index/pdf/10.1007/s12257-012-0545-9; https://dx.doi.org/10.1007/s12257-012-0545-9; https://link.springer.com/article/10.1007/s12257-012-0545-9
Springer Science and Business Media LLC
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