PlumX Metrics
Embed PlumX Metrics

Quantitative measurement of the mechanical properties of human antibodies with sub-10-nm resolution in a liquid environment

Nano Research, ISSN: 1998-0000, Vol: 8, Issue: 6, Page: 1987-1996
2015
  • 24
    Citations
  • 14
    Usage
  • 32
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

The nanomechanical properties of single human immunoglobulin G and M antibodies were measured in a liquid environment using a fast force-volume technique with sub-10-nm spatial resolution. The ultrastructural details of these molecules were resolved in the images. Simultaneously, important physical properties, including elasticity, adhesion, and deformation were measured. The dimensions and adsorption of the immunoglobulin M antibodies onto the substrate indicated that they are highly flexible. The antibodies were characterized by a low elastic stiffness (34 ± 10 MPa) and high deformability (1.5 ± 0.5 nm). [Figure not available: see fulltext.]

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know