The value of local normal limits in quantitative Thallium-201 CZT MPI SPECT
Journal of Nuclear Cardiology, ISSN: 1071-3581, Vol: 24, Issue: 2, Page: 672-682
2017
- 4Citations
- 13Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations4
- Citation Indexes4
- CrossRef4
- Captures13
- Readers13
- 13
Article Description
Considering the distinctive characteristics of CZT detectors, automatic quantification of ischemia using normal limits included with software package may deliver suboptimal results for CAD detection. The present study aims to evaluate the benefits of creating normal limits specific to a local population and laboratory protocol. Two groups were selected from patients who had undergone a CZT MPI. Normal limits were generated with the QPS application based on the population with low likelihood of CAD. Using the vendor-supplied and the population-specific normal limits i-TPD and vessel-specific SDS results obtained for patients who had subsequently undergone coronary angiography were compared with coronary angiography data. A weak correlation was observed for low i-TPD (stress TPD minus rest TPD) and SDS values. Both databases gave similar values for the area under the ROC curve concerning i-TPD (0.75 to 0.74) and SDS results (0.72 to 0.75 for the LAD, 0.62 to 0.64 for the LCx, and 0.63 to 0.67 for the RCA). Sensitivity (60%), specificity (78%), and predictive positive (84%) and negative (52%) values were also similar with a diagnostic and prognostic threshold value. The use of a population-specific created database did not influence the diagnostic value of thallium-201 MPI QPS results using a CZT camera.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1071358123065017; http://dx.doi.org/10.1007/s12350-016-0430-6; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84959542432&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/26936035; https://linkinghub.elsevier.com/retrieve/pii/S1071358123065017; https://dx.doi.org/10.1007/s12350-016-0430-6; http://link.springer.com/content/pdf/10.1007/s12350-016-0430-6.pdf; https://link.springer.com/content/pdf/10.1007/s12350-016-0430-6.pdf; https://link.springer.com/article/10.1007/s12350-016-0430-6; http://link.springer.com/content/pdf/10.1007/s12350-016-0430-6; http://link.springer.com/10.1007/s12350-016-0430-6; https://link.springer.com/content/pdf/10.1007%2Fs12350-016-0430-6.pdf; http://link.springer.com/article/10.1007/s12350-016-0430-6/fulltext.html; https://link.springer.com/article/10.1007%2Fs12350-016-0430-6
Elsevier BV
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