Active surveillance for prostate cancer: comparison of PRIAS-eligible and PRIAS-ineligible patients
Tijdschrift voor Urologie, ISSN: 2211-4718, Vol: 10, Issue: 1, Page: 9-16
2020
- 3Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Captures3
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Article Description
Little is known about the outcomes of off-protocol selected prostate cancer patients who opt for active surveillance. In our cohort of 1,000 patients, outcomes of PRIAS-eligible patients were compared with outcomes of PRIAS-ineligible patients. Unfavourable outcomes after radical prostatectomy (RP) and risk of metastasis were evaluated. 50% of patients on AS did not comply with the PRIAS criteria. PRIAS-ineligible patients discontinued active surveillance due to tumour progression significantly earlier than PRIAS-eligible patients; they also had a higher risk of positive surgical margins and unfavourable histology after deferred RP. PSA density ≥ 0.2 was the most important individual predictor and, in addition to a higher risk of tumour progression and unfavourable surgical outcomes, was also associated with a significantly higher risk of biochemical progression after deferred radical prostatectomy and a higher risk of metastasis.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85073790091&origin=inward; http://dx.doi.org/10.1007/s13629-019-00266-7; http://link.springer.com/10.1007/s13629-019-00266-7; http://link.springer.com/content/pdf/10.1007/s13629-019-00266-7.pdf; http://link.springer.com/article/10.1007/s13629-019-00266-7/fulltext.html; https://dx.doi.org/10.1007/s13629-019-00266-7; https://link.springer.com/article/10.1007/s13629-019-00266-7
Springer Science and Business Media LLC
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