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Anesthesia for Long QT Syndrome

Current Anesthesiology Reports, ISSN: 1523-3855, Vol: 11, Issue: 4, Page: 483-489
2021
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Review Description

Purpose of Review: This review article seeks to discuss the salient information about the known genetic variants associated with congenital long QT syndrome (LQTS) and describe the current anesthetic considerations. Recent Findings: LQTS describes a heterogeneous group of patients with varying genetic mutations that cause an increased risk of torsade de pointe and sudden death. Research continues to identify more genetic mutations associated with LQTS subtypes. Publications of clinical experience with LQTS patients under general anesthesia provide new insights on the risk of medication inducing arrhythmias in these patients. Summary: Many medications used during general anesthesia are known to prolong the QTc interval. Patients with LQTS are at increased risk of arrhythmias under general anesthesia.

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