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The Role and Diagnosis of Allergic Contact Dermatitis in Patients with Atopic Dermatitis

American Journal of Clinical Dermatology, ISSN: 1179-1888, Vol: 19, Issue: 3, Page: 293-302
2018
  • 127
    Citations
  • 0
    Usage
  • 203
    Captures
  • 3
    Mentions
  • 7
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    127
  • Captures
    203
  • Mentions
    3
    • News Mentions
      3
      • 3
  • Social Media
    7
    • Shares, Likes & Comments
      7
      • Facebook
        7

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Article Description

Patients with atopic dermatitis (AD) have increased penetration of allergens, immune dysregulation (including shared cytokine pathways), and frequent use of emollients and topical medications, all of which may predispose toward developing allergic contact dermatitis (ACD). Recent systematic reviews have suggested that ACD is a significant clinical problem in both children and adults with AD. While this remains controversial, ACD remains an important comorbidity and potential exacerbant of AD in clinical practice. Common relevant allergens, include lanolin, neomycin, formaldehyde, sesquiterpene lactone mix, compositae mix, and fragrances that are commonly found in AD patients’ personal care products. We herein review the clinical scenarios where patch testing is indicated in AD. In addition, we review the contraindications, preferred patch-testing series, pitfalls, and challenges determining the relevance of positive patch-test reactions in AD patients.

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