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Abrocitinib: First Approval

Drugs, ISSN: 1179-1950, Vol: 81, Issue: 18, Page: 2149-2157
2021
  • 76
    Citations
  • 0
    Usage
  • 42
    Captures
  • 1
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    76
  • Captures
    42
  • Mentions
    1
    • News Mentions
      1
      • 1
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Most Recent News

Successful Treatment of Granulomatous Rosacea by JAK Inhibitor Abrocitinib: A Case Report

Background Rosacea is a chronic inflammatory skin disease characterized by facial erythema, papules, pustules, capillary dilation, and flushing. Commonly observed in middle-aged and elderly individuals,

Review Description

Abrocitinib (Cibinqo) is an oral small-molecule inhibitor of Janus kinase 1 (JAK1) being developed by Pfizer for the treatment of moderate-to-severe atopic dermatitis (AD). In September 2021, abrocitinib was approved in the UK and Japan for the treatment of moderate-to-severe AD in adults and adolescents 12 years and older who are candidates for systemic therapy. Abrocitinib has also received a positive CHMP opinion in the EU for the treatment of moderate-to-severe atopic dermatitis in adults who are candidates for systemic therapy. Regulatory applications for the drug have also been submitted for review to several other countries, including the USA and Australia. This article summarizes the milestones in the development of abrocitinib leading to this first approval for the treatment of moderate-to-severe AD.

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