Immunocompromised Patients with Protracted COVID-19: a Review of “Long Persisters”
Current Transplantation Reports, ISSN: 2196-3029, Vol: 9, Issue: 4, Page: 209-218
2022
- 43Citations
- 27Captures
- 5Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations43
- Citation Indexes43
- 43
- Captures27
- Readers27
- 27
- Mentions5
- News Mentions5
- 5
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Review Description
Purpose of Review: Certain immunocompromised individuals are at risk for protracted COVID-19, in which SARS-CoV-2 leads to a chronic viral infection. However, the pathogenesis, diagnosis, and management of this phenomenon remain ill-defined. Recent Findings: Herein, we review key aspects of protracted SARS-CoV-2 infection in immunocompromised individuals, or the so-called long persisters, and describe the clinical presentation, risk factors, diagnosis, and treatment modalities of this condition, as well as intra-host viral evolution. Based on the available data, we also propose a framework of criteria with which to approach this syndrome. Summary: Protracted COVID-19 is an uncharacterized syndrome affecting patients with B-cell depletion; our proposed diagnostic approach and definitions will inform much needed future research.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85141659176&origin=inward; http://dx.doi.org/10.1007/s40472-022-00385-y; http://www.ncbi.nlm.nih.gov/pubmed/36407883; https://link.springer.com/10.1007/s40472-022-00385-y; https://dx.doi.org/10.1007/s40472-022-00385-y; https://link.springer.com/article/10.1007/s40472-022-00385-y
Springer Science and Business Media LLC
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