PlumX Metrics
Embed PlumX Metrics

Tumor microenvironment heterogeneity: challenges and opportunities.

Current molecular biology reports, ISSN: 2198-6428, Vol: 3, Issue: 4, Page: 218-229
2017
  • 75
    Citations
  • 0
    Usage
  • 130
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

The tumor microenvironment (TME) has been recognized as an integral component of malignancies in breast and prostate tissues, contributing in confounding ways to tumor progression, metastasis, therapy resistance and disease recurrence. Major components of the TME are immune cells, fibroblasts, pericytes, endothelial cells, mesenchymal stroma/stem cells (MSCs), and extracellular matrix (ECM) components. Herein, we discuss the molecular and cellular heterogeneity within the TME and how this presents unique challenges and opportunities for treating breast and prostate cancers.

Bibliographic Details

F. Runa; S. Hamalian; K. Meade; P. Shisgal; P. C. Gray; J. A. Kelber

Springer Science and Business Media LLC

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know