PlumX Metrics
Embed PlumX Metrics

Regulation of Fibroblast Growth Factor 23 by Iron, EPO, and HIF.

Current molecular biology reports, ISSN: 2198-6428, Vol: 5, Issue: 1, Page: 8-17
2019
  • 17
    Citations
  • 0
    Usage
  • 28
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

Fibroblast growth factor-23 (FGF23) is the key hormone produced in bone critical for phosphate homeostasis. Elevated serum phosphorus and 1,25dihydroxyvitaminD stimulates FGF23 production to promote renal phosphate excretion and decrease 1,25dihydroxyvitaminD synthesis. Thus completing the feedback loop and suppressing FGF23. Unexpectedly, studies of common and rare heritable disorders of phosphate handling identified links between iron and FGF23 demonstrating novel regulation outside the phosphate pathway.

Bibliographic Details

Wheeler, Jonathan A; Clinkenbeard, Erica L

Springer Science and Business Media LLC

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know