The activity of pyruvate carrier in a reconstituted system: Substrate specificity and inhibitor sensitivity
Archives of Biochemistry and Biophysics, ISSN: 0003-9861, Vol: 297, Issue: 1, Page: 162-168
1992
- 19Citations
- 13Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations19
- Citation Indexes19
- CrossRef19
- 19
- Captures13
- Readers13
- 13
Article Description
The pyruvate carrier, of molecular mass 34 kDa, was purified from mitochondria isolated from rat liver, rat brain, and bovine heart, by affinity chromatography on immobilized 2-cyano-4-hydroxycinnamate. Its activity after reconstitution in phosphatidylcholine vesicles was measured either as uptake of [1- 14 C]pyruvate or as exchange with different 2-oxoacids. All preparations exhibited similar apparent K m values for pyruvate, but somewhat different V max values. The ability to exchange different anions of physiological significance, including branched-chain 2-oxoacids, confirmed the known substrate specificity described for the pyruvate carrier in mitochondria. The sensitivity of pyruvate transport toward phenylglyoxal suggested an important role of arginyl residues in the transport activity, while a role of lysyl and histydyl residues was not confirmed.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/000398619290655G; http://dx.doi.org/10.1016/0003-9861(92)90655-g; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0026705820&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/1637179; https://linkinghub.elsevier.com/retrieve/pii/000398619290655G; http://linkinghub.elsevier.com/retrieve/pii/000398619290655G; http://api.elsevier.com/content/article/PII:000398619290655G?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:000398619290655G?httpAccept=text/plain; http://dx.doi.org/10.1016/0003-9861%2892%2990655-g; https://dx.doi.org/10.1016/0003-9861%2892%2990655-g
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know