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Distribution of PZ-peptidase and glycylprolyl β-naphthylamidase activities in oral tissues

Archives of Oral Biology, ISSN: 0003-9969, Vol: 20, Issue: 1, Page: 19-22
1975
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The activity of a peptidase (PZ-peptidase) acting on a synthetic collagenase substrate, 4-phenylazobenzyloxycarbonyl-L-prolyl-L-leucyl-glycyl-L-prolyl-D-arginine and the activity of a peptidase (glycylprolyl β-naphthylamidase) acting on glycyl-L-prolyl β-naphthylamide, were examined in bovine and human oral tissues and in rat experimental granuloma. Both enzyme activities were high in the dental follicle beneath the deciduous tooth undergoing resorption, and they were increased in the developing rat granuloma tissue. However, human submaxillary gland and human duct saliva contained only glycylprolyl β-naphthylamidase activity.

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