Modification by clofibric acid of acyl composition of glycerolipids in rat liver
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, ISSN: 0005-2760, Vol: 795, Issue: 3, Page: 543-551
1984
- 43Citations
- 2Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations43
- Citation Indexes43
- 43
- CrossRef33
- Captures2
- Readers2
Article Description
Administration of p -chlorophenoxyisobutyric acid (clofibric acid) to rats induced a marked change in acyl composition of hepatic glycerolipids; a considerable increase in the proportion of octadecenoic acid (18:1) was accompanied by a marked decrease in the proportion of octadecadienoic acid (18:2). Among the glycerolipids, the changes in the proportions of 18:1 and 18:2 were the most marked in phosphatidylcholine. The change in the acyl composition of phosphatidylcholine paralleled the change in free fatty acid composition in microsomes. The treatment of rats with clofibric acid resulted in a 2.3-fold increase in activity of microsomal palmitoyl-CoA chain elongation and a 4.8-fold increase in activity of stearoyl-CoA desaturation. The activities of acyl-CoA synthetase, 1-acylglycerophosphate acyltransferase and 1-acylgly-cerophosphorylcholine acyltransferase in hepatic microsomes were increased approx. 3-, 1.7- and 3.6-times, respectively, by the treatment of rats with clofibric acid. These findings are discussed with respect to the role of fatty acid modification systems in the regulation of acyl composition of phosphatidylcholine.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/000527608490184X; http://dx.doi.org/10.1016/0005-2760(84)90184-x; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0021173496&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/6477960; https://linkinghub.elsevier.com/retrieve/pii/000527608490184X; http://linkinghub.elsevier.com/retrieve/pii/000527608490184X; http://api.elsevier.com/content/article/PII:000527608490184X?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:000527608490184X?httpAccept=text/plain; http://dx.doi.org/10.1016/0005-2760%2884%2990184-x; https://dx.doi.org/10.1016/0005-2760%2884%2990184-x
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know