PlumX Metrics
Embed PlumX Metrics

cAMP-dependent induction of δ-aminolevulinate synthase in isolated embryonic chick liver cells

Biochemical and Biophysical Research Communications, ISSN: 0006-291X, Vol: 90, Issue: 1, Page: 42-49
1979
  • 8
    Citations
  • 0
    Usage
  • 0
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

Isolated liver cells were prepared from 17-day old chick embryos and incubated in Eagle's basal medium. Induction of δ-aminolevulinate synthase activity occurred immediately upon addition of allylisopropylacetamide and was totally dependent on the presence of Bt 2 cAMP (or cAMP) during the first 6 h of incubation. Under optimal inducing conditions in the presence of desferrioxamine mesylate and hormones, δ-aminolevulinate synthase induction occurred at rates comparable with those observed in ovo. The isolated liver cells provide a convenient experimental system for studying the effect of porphyrogenic drugs on porphyrin metabolism.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know