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Studies on rat cytokines as mediators of the acute phase response

Biochemical and Biophysical Research Communications, ISSN: 0006-291X, Vol: 112, Issue: 1, Page: 14-19
1983
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Article Description

A cytokine preparation from rat peritoneal exudate cells was studied. The preparation was pronase sensitive and heat labile, but was insensitive to trypsin treatment. Administration to rats resulted in elevated serum levels of α 1 -acid glycoprotein, sialyltransferase activities and cortisol, but depressed serum albumin levels; in addition, hepatic sialyltransferase activities were increased and hepatic β-galactosidase and β-N-acetylhexosaminidase activities were depressed.

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