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Thermotropic change in phospholipid packing in microsomal membranes sensed by phospholipase A 2

Chemistry and Physics of Lipids, ISSN: 0009-3084, Vol: 34, Issue: 2, Page: 153-161
1984
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Article Description

A reversible, temperature-dependent change in phospholipid packing occurring between 0°C and 12°C has been identified in microsomal membranes by the use of phospholipase A 2 from Crotalus atrox. It manifests itself as a drastic increase in susceptibility to the phospholipase and depends on non-lipid (presumably protein) membrane components. It is suggested that this change could underlie the change in transmembrane mobility of phospholipids which occurs in the same temperature range.

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