Influence of alkali metal cations on the transport of calcium by phosphatidate in multi-phase systems
Chemistry and Physics of Lipids, ISSN: 0009-3084, Vol: 54, Issue: 3, Page: 221-232
1990
- 6Citations
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Metrics Details
- Citations6
- Citation Indexes6
- CrossRef4
Article Description
The effects of alkali metal cations on the rates at which Ca 2+ and phosphatidic acid were cotransported from aqueous to hydrocarbon medium were examined. The alkali metal cations remained in the aqueous phase yet specifically influenced the transport of Ca 2+ into the hydrocarbon solvent. For the physiological cations, Na + and K +, there were critical concentration ranges in which small changes in concentration effected sharp changes in transport rates. The maximal rate observed with Na + was an order of magnitude greater than that with K + ; however, unlike Na +, K + promoted low levels of transport below the critical concentration range. Li + effected only low levels of transport even at high concentrations, whereas Rb + and Cs + induced transport at rates proportional to their concentrations. These results are discussed in terms of a classical ionophore model for the complex composed of a neutral phosphatidic acid dimer bridged by Ca 2+.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/000930849090015J; http://dx.doi.org/10.1016/0009-3084(90)90015-j; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0025371577&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/2225238; http://linkinghub.elsevier.com/retrieve/pii/000930849090015J; http://api.elsevier.com/content/article/PII:000930849090015J?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:000930849090015J?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/000930849090015J; http://dx.doi.org/10.1016/0009-3084%2890%2990015-j; https://dx.doi.org/10.1016/0009-3084%2890%2990015-j
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