Effects of cytochalasin and alkaloid drugs on the biological expression of herpes simplex virus type 2 DNA
Experimental Cell Research, ISSN: 0014-4827, Vol: 103, Issue: 1, Page: 15-22
1976
- 9Citations
- 1Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations9
- Citation Indexes9
- CrossRef9
- Captures1
- Readers1
Article Description
Pretreatment of rabbit kidney cells with cytochalasins B and D (CB, CD) enhanced herpes simplex virus type 2 (HSV-2) DNA infectivity 3- to 6-fold over values obtained using the standard CaCl 2 technique. Cells were pretreated with CB for 4–6 h to achieve infectivity enhancement. A lower concentration of CD, and shorter pretreatment periods, resulted in comparable DNA infectivity. Separate exposure of cells to colchicine, colcemid, or vinblastine increased DNA infectivity 7-, 6-, and 5-fold, respectively, over control values. Additional enhancement was obtained when CD was used together with any one of the aforementioned drugs. Maximal enhancement of HSV-2 DNA infectivity was obtained by pretreating recipient cells with a drug mixture containing colchicine, colcemid, and CD. This treatment maximized infectivity levels 20- to 30-fold over CaCl 2 control values.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0014482776902354; http://dx.doi.org/10.1016/0014-4827(76)90235-4; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0017034527&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/186287; https://linkinghub.elsevier.com/retrieve/pii/0014482776902354; http://dx.doi.org/10.1016/0014-4827%2876%2990235-4; https://dx.doi.org/10.1016/0014-4827%2876%2990235-4
Elsevier BV
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