The distribution of apo C-II and apo C-III in very low density lipoproteins of normal and type iv subjects
Atherosclerosis, ISSN: 0021-9150, Vol: 35, Issue: 4, Page: 419-424
1980
- 31Citations
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Article Description
The apoC-II/apoC-III ratio and the distribution of C apoproteins as percentage of the total protein in VLDL obtained from normolipidemic and type IV patients was studied by analytical isoelectrofocusing. While the percentage concentration of apoC-III was unchanged that of apoC-II was 9.2% of total protein in normal VLDL and only 7.4% in type IV VLDL ( P < 0.05). The apoC-II/apoC-III ratio significantly decreased in type IV patients. The analysis of VLDL subfractions obtained by density gradient ultracentrifugation gave essentially the same results. These data confirm the decrease of apoC-II as % of the protein in type IV VLDL and suggest that the decrease of the apoC-II/apoC-III ratio in type IV patients is related only to the decreased content of apoC-II. Whether the reduced apoC-II percentage amount or the decreased apoC-II/apoC-III ratio are related to the hypertriglyceridemia in type IV subjects is still unclear.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0021915080901823; http://dx.doi.org/10.1016/0021-9150(80)90182-3; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0018833660&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/7378122; https://linkinghub.elsevier.com/retrieve/pii/0021915080901823; http://dx.doi.org/10.1016/0021-9150%2880%2990182-3; https://dx.doi.org/10.1016/0021-9150%2880%2990182-3
Elsevier BV
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