The use of a hapten-Fab conjugate to sensitive target cells for antibody-dependent complement-mediated lysis and antibody-dependent cell-mediated cytotoxicity
Journal of Immunological Methods, ISSN: 0022-1759, Vol: 136, Issue: 2, Page: 185-191
1991
- 13Citations
- 7Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations13
- Citation Indexes13
- 13
- CrossRef12
- Captures7
- Readers7
Article Description
NIP-conjugated Fab' fragments from a rabbit hyperimmunized with sheep red blood cells (SRBC) were used to link the hapten NIP to target cells for antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent complement-mediated lysis (ADCML). Target cells (SRBC) labelled with this NIP-Fab' complex were compared with SRBC directly haptenized with NIP in ADCC and ADCL assays using a NIP specific IgG1 chimeric antibody. Both methods yielded almost identical results. Using the NIP-Fab' conjugate identical target cell haptenization was readily achieved from experiment to experiment. Using conjugates of different NIP/Fab' ratios it should be possible to study how such changes influence antibody effector functions.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/002217599190005Z; http://dx.doi.org/10.1016/0022-1759(91)90005-z; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0025966843&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/1999650; http://linkinghub.elsevier.com/retrieve/pii/002217599190005Z; http://api.elsevier.com/content/article/PII:002217599190005Z?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:002217599190005Z?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/002217599190005Z; http://dx.doi.org/10.1016/0022-1759%2891%2990005-z; https://dx.doi.org/10.1016/0022-1759%2891%2990005-z
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know