The influence of multiple mutagenic treatments on the occurrence of 6-thioguanine-resistant mutants in dividing V79 cells
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, ISSN: 0027-5107, Vol: 159, Issue: 1, Page: 91-97
1986
- 11Citations
- 3Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations11
- Citation Indexes11
- CrossRef11
- 11
- Captures3
- Readers3
Article Description
Repeated treatments of dividing Chinese hamster V79 cells with ultraviolet radiation or a simple monofunctional alkylating agent (methyl methanesulphonate, N -methyl- N ′-nitr- N -nitrosoguanidine or N -methyl- N -nitrosourea) were studied with regard to the pattern of cumulative increase of 6-thioguanine-resistant mutants in the surviving population. There were 5–10 divisions of surviving cells between two successive treatments. Repeated treatments with different agents produced different effects. The observed results indicating either a higher or lower than additive effect of single doses may be explained by induced repair process.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0027510786901168; http://dx.doi.org/10.1016/0027-5107(86)90116-8; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0022575470&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/3941668; https://linkinghub.elsevier.com/retrieve/pii/0027510786901168; http://dx.doi.org/10.1016/0027-5107%2886%2990116-8; https://dx.doi.org/10.1016/0027-5107%2886%2990116-8
Elsevier BV
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