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Circadian rhythms in sleep-wakefulness and wheel-running activity in a congenitally anophthalmic rat mutant

Physiology & Behavior, ISSN: 0031-9384, Vol: 39, Issue: 3, Page: 321-326
1987
  • 19
    Citations
  • 0
    Usage
  • 9
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    19
    • Citation Indexes
      19
  • Captures
    9

Article Description

Circadian rhythms were examined in a congenitally anophthalmic rat mutant. All bilaterally anophthalmic rats had clear circadian rhythms in sleep-wakefulness as well as in locomotor activity, but the rhythms did not entrain to the light-dark (LD) cycle. However, two unilaterally anophthalmic rats, like sighted rats, reentrained their sleep-wakefulness rhythms to the LD cycle in 4 days after a 6 hr delaying phase-shift. The hypogenesis of the suprachiasmatic nuclei (SCN) that is correlated with absence of circadian activity rhythms in anophthalmic mice was not observed in these anophthalmic rats.

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