Alveolar-arterial equilibration in the lung of sheep
Respiration Physiology, ISSN: 0034-5687, Vol: 55, Issue: 2, Page: 205-221
1984
- 4Citations
- 5Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations4
- Citation Indexes4
- CrossRef4
- Captures5
- Readers5
Article Description
In order to compare the efficiency of sheep lung with that of dog, gaseous exchange in hypoxia (F I O2 0.12–0.13) with and without CO in the inspired air (F I CO 0.001) was measured in 12 sheep (mean body weight = 30.4 kg) under pentothal anesthesia and artificial ventilation. Alveolar-arterial pressure difference of O 2, % venous admixture and amount of V A /Q inhomogeneity were found to be substantially larger than in dog. Steady-state pulmonary diffusing capacity estimates, computed by three different procedures were, both for O 2 and for CO, about 40% smaller than in dog. The Dt O2 /Dl CO ratio were not significantly different from those determined on dog data; thus the presumed benefecial effect of sheep small erythrocytes on O 2 transfer could not be demonstrated. Because its DL O2 /M O2 ratio is lower than that of dog, sheep appears to be more adequate than dog as a model for human alveolar-arterial gas exchange.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0034568784900239; http://dx.doi.org/10.1016/0034-5687(84)90023-9; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0021361760&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/6427872; https://linkinghub.elsevier.com/retrieve/pii/0034568784900239; http://dx.doi.org/10.1016/0034-5687%2884%2990023-9; https://dx.doi.org/10.1016/0034-5687%2884%2990023-9
Elsevier BV
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