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Enzyme induction by oxygen in the accumulation of cytochrome P -450 during batch fermentations in 20% d -glucose with Saccharomyces cerevisiae

Enzyme and Microbial Technology, ISSN: 0141-0229, Vol: 7, Issue: 11, Page: 553-556
1985
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  • Citations
    7
    • Citation Indexes
      7

Article Description

Production of cytochrome P -450 [RH, reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating), EC 1.14.14.1] by Saccharomyces cerevisiae NCYC 754, grown in batch culture on 20% d -glucose medium, was markedly affected by the speed of the orbital shaker. Oxygenation rather than agitation was confirmed as the likely cause of this effect using an optimized system in a microprocessor-controlled 4 litre batch fermenter. Oxygen may be acting as a substrate inducer of the cytochrome P -450 in this yeast.

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