Chromatid-type aberrations induced by Alu I in Chinese hamster ovary cells
Mutation Research/Genetic Toxicology, ISSN: 0165-1218, Vol: 299, Issue: 3, Page: 305-311
1993
- 8Citations
- 7Captures
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Article Description
Treatment of CHO cells with Alu I in the S-phase leads to chromatid-type aberrations whose frequencies are linearly correlated with dose. Treatment in the S-phase leads to fewer aberrations than treatment in the G1-phase, which is comparable to chromosomal aberration induction following X-irradiation in the G1-and S-phases. Treatment in the G1-phase leads to few chromatid-type interchanges, some of these may originate from DNA single-strand gaps induced by Alu I in canonical structures of DNA and in DNA · RNA hybrids.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/016512189390107O; http://dx.doi.org/10.1016/0165-1218(93)90107-o; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027399292&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/7683098; http://linkinghub.elsevier.com/retrieve/pii/016512189390107O; http://api.elsevier.com/content/article/PII:016512189390107O?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:016512189390107O?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/016512189390107O; http://dx.doi.org/10.1016/0165-1218%2893%2990107-o; https://dx.doi.org/10.1016/0165-1218%2893%2990107-o
Elsevier BV
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