Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus
Vaccine, ISSN: 0264-410X, Vol: 11, Issue: 2, Page: 267-272
1993
- 28Citations
- 23Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations28
- Citation Indexes28
- 28
- CrossRef24
- Captures23
- Readers23
- 23
Article Description
An infection of pigs with the porcine respiratory coronavirus (PRCV) induces antibodies which neutralize the enteropathogenic transmissible gastroenteritis virus (TGEV) and PRCV to the same titre. In the present study, 10-week-old seronegative pigs ( n = 8), pigs immune following TGEV inoculation ( n = 4) or pigs immune following aerosol ( n = 8) or intragastric inoculation ( n = 4) with PRCV were challenged with TGEV. Whereas TGEV-immune pigs were completely protected against challenge, all PRCV-immune pigs showed serological evidence of TGEV replication. Nevertheless, the aerosol or intragastric inoculation with PRCV primed the humoral immune system against TGEV and the TGEV challenge induced a secondary antibody response in most PRCV-immune pigs. Furthermore, all PRCV-immune pigs showed a decrease in the duration of the excretion of infectious TGEV (0–4 days) in comparison with the duration of the virus excretion by seronegative pigs (5–6 days).
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0264410X9390028V; http://dx.doi.org/10.1016/0264-410x(93)90028-v; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027526006&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/8382421; https://linkinghub.elsevier.com/retrieve/pii/0264410X9390028V; http://linkinghub.elsevier.com/retrieve/pii/0264410X9390028V; http://api.elsevier.com/content/article/PII:0264410X9390028V?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:0264410X9390028V?httpAccept=text/plain; http://dx.doi.org/10.1016/0264-410x%2893%2990028-v; https://dx.doi.org/10.1016/0264-410x%2893%2990028-v
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