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Calcium homeostasis of epithelial cells

Comparative Biochemistry and Physiology Part A: Physiology, ISSN: 0300-9629, Vol: 90, Issue: 4, Page: 767-770
1988
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1.1. Cytosolic free Ca2+ is an important regulator of ion transport processes in epithelial cells.2.2. Free Ca2+ concentration is regulated by a concerted action of Ca2+ transport systems in plasma membranes and intracellular organelles.3.3. These transport systems were studied in intestinal and renal cortical cells with emphasis on the transport capacities and Ca2+ affinities.4.4. Ca2+ accumulation by permeabilized cells was compared to Ca2+ uptake by isolated organelles and membrane fractions.5.5. Effects induced by cell or organelle isolation methods and the influence of temperature and pH on Ca2+ transport capacities were studied.

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